报告题目：Application of Biologically Inspired Materials in Orthopaedics
报 告 人：Dr. Hang Lin, 美国匹兹堡大学
报告时间：2017年10月26日（周四）上午10:00
报告地点：材料楼210会议室
报告人简介：
Dr. Hang Lin is an Assistant Professor in Department of Orthopaedic Surgery at the University of Pittsburgh. He is also a member faculty in the McGowan Institute for Regenerative Medicine.
Dr. Lin received a PhD in Cell Biology from the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences. From 2008-2010, Dr. Lin was a Visiting Fellow at the National Institutes of Health, Bethesda, MD. He has been with the University of Pittsburgh since 2010. Currently, Dr. Lin has published 36 peer-reviewed articles and 2 book chapters. He also holds 4 patents, with other 5 in pending.
Dr. Lin’s research interests focus on the study of articular joint diseases and the development of efficacious treatments to regenerate injured tissues. For example, he had developed a method to apply visible light-based projection stereolithography (3D printing) on live cell fabrication. These 3D printed constructs can be further activated through the inclusion of vectors carrying therapeutic factors (Gene-activated matrix/scaffold). Working with other collaborators, he had developed micro-physiological osteochondral tissues (mOCs) in vitro, which offer novel capabilities for investigating the physiology of osteochondral tissue and the pathogenic mechanisms of osteoarthritis (OA), and serving as a high-throughput platform to test potential drugs for OA treatment. Currently, his lab is divided into 3 branches:
1）Tissue chip modeling of synovial joint pathologies: effects of inflammation and adipose-mediated diabetic complications.
2）Mechanisms of MSC responses to substrate rigidity of scaffolds – Enhancing cell quality for tissue regeneration.
3）Effect of chondrocyte aging on their regeneration potential and OA pathology.